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Nature Medicine

Effects of daily multivitamin–multimineral and cocoa extract supplementation on epigenetic aging clocks in the COSMOS randomized clinical trial

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Nature Medicine, Published online: 09 March 2026; doi:10.1038/s41591-026-04239-3 In a prespecified ancillary analysis of the COSMOS randomized trial, supplementation with daily multivitamins, but not with cocoa extract, over the course of 2 years decreased biological aging, as measured by epigenetic aging clocks.

Nature Medicine, Published online: 09 March 2026;

doi:10.1038/s41591-026-04239-3

In a prespecified ancillary analysis of the COSMOS randomized trial, supplementation with daily multivitamins, but not with cocoa extract, over the course of 2 years decreased biological aging, as measured by epigenetic aging clocks.

— Source: Nature Medicine (https://www.nature.com/articles/s41591-026-04239-3)

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