Breaking Breaking
Nature Medicine

A structure-based mRNA vaccine for Nipah virus in healthy adults: a phase 1 trial

myndfocal
Nature Medicine, Published online: 12 March 2026; doi:10.1038/s41591-026-04265-1 In this phase 1, open-label dose-escalation study in healthy adults found that the mRNA vaccine (mRNA-1215), encoding the Nipah virus Malaysian strain chimeric pre-fusion F protein linked to glycoprotein G, was safe and induced elevated immune responses at 1 year of follow-up, indicating that this is a promising vaccine candidate for further development.

Nature Medicine, Published online: 12 March 2026;

doi:10.1038/s41591-026-04265-1

In this phase 1, open-label dose-escalation study in healthy adults found that the mRNA vaccine (mRNA-1215), encoding the Nipah virus Malaysian strain chimeric pre-fusion F protein linked to glycoprotein G, was safe and induced elevated immune responses at 1 year of follow-up, indicating that this is a promising vaccine candidate for further development.

— Source: Nature Medicine (https://www.nature.com/articles/s41591-026-04265-1)

Health Science
Read original on Nature Medicine →