Nature Medicine, Published online: 17 March 2026; doi:10.1038/s41591-026-04217-9 In a double-blind, cluster-randomized, placebo-controlled trial in Niger that examined azithromycin mass drug distribution in different age groups of children, there was evidence of selection of macrolide resistance determinants in the gut in children 1 to 59 months old, but resistance to other classes of antibiotics were not observed in the gut or nasopharynx.
Nature Medicine, Published online: 17 March 2026;
doi:10.1038/s41591-026-04217-9
In a double-blind, cluster-randomized, placebo-controlled trial in Niger that examined azithromycin mass drug distribution in different age groups of children, there was evidence of selection of macrolide resistance determinants in the gut in children 1 to 59 months old, but resistance to other classes of antibiotics were not observed in the gut or nasopharynx.
— Source: Nature Medicine (https://www.nature.com/articles/s41591-026-04217-9)