Want to keep track of the largest startup funding deals in 2025 with our curated list of $100 million-plus venture deals to U.S.-based companies? Check out T
he Crunchbase Megadeals Board
.
This is a weekly feature that runs down the week’s top 10 announced funding rounds in the U.S. Check out last week’s biggest funding deal roundup
here
.
This week featured a lot of funding deals with a lot of zeroes on the end. Generative AI powerhouse
Anthropic
, of course, boasted the most zeroes with its $30 billion Series G, the second-largest venture funding round of all time. Other big fundraisers included robotics startup
Apptronik
, fusion innovator
Inertia Enterprises
, and space tech unicorn
Axiom Space
.
1.
Anthropic
, $30B, Generative AI:
Anthropic
raised $30 billion
in a massive Series G funding round that values the San Francisco-based generative AI company at $380 billion post-money. The financing marks
the largest venture funding deal of 2026
so far and the second-largest of all time, per Crunchbase data.
GIC
and
Coatue
led the raise, which was also “co-led” by
D.E. Shaw & Co. Ventures
,
Dragoneer Investment Group
,
Founders Fund
,
Iconiq Capital
and
MGX
, according to the company.
2.
Apptronik
, $520M, humanoid robots:
AI-powered robotics company Apptronik added $520 million in new financing in an extension of its $415 million Series A raise in February 2025, The investment brings the total round to over $935 million for the Austin-based company.
3.
Inertia Enterprises
, $450M, fusion energy:
Livermore, California-based fusion power startup Inertia Enterprises announced that it secured
$450 million in Series A funding
.
Bessemer Venture Partners
led the round for the 2-year-old company, joined by
Google Ventures
,
Threshold
and other backers.
4.
Axiom Space
, $350M, space tech:
Axiom Space, a startup that is building a successor to the International Space Station and developing spacesuits for a moon mission, closed on $350 million in new financing.
Type One Ventures
and
Qatar Investment Authority
led the round for the Houston-based company.
5.
Runway
, $315M, AI:
Runway, an AI research and technology startup, picked up
$315 million in a Series E
round.
General Atlantic
led the financing, which set a $5.3 billion valuation for the New York-based company, up from $3.3 billion last April.
6.
Talkiatry
, $210M, mental health:
Talkiatry, a provider of in-network psychiatry services to health systems and employers, picked up $210 million in Series D funding, led by
Perceptive Advisors
. The round brings total funding to date for the New York-based company to more than $400 million.
7.
Solace Health
, $130M, healthcare:
Redwood City, California-based Solace Health, a digital platform that connects patients with expert healthcare advocates, raised $130 million in Series C funding.
IVP
led the financing, which set a valuation of over $1 billion for the 4-year-old company.
8.
Garner Health
, $118M, healthcare:
Garner Health, a digital platform that helps patients find healthcare providers, raised $118 million in Series D financing.
Kleiner Perkins
led the round for the New York-based company.
9. (tied)
Simile
, $100M, AI simulation:
Palo Alto, California-based Simile, a startup focused on applying AI to create simulated environments and simulation tools with AI agents, raised $100 million in Series A funding led by
Index Ventures
.
9. (tied)
Loyal
, $100M, dog longevity:
Loyal, a startup focused on drugs to extend healthy lifespans in senior dogs, raised $100 million in Series C funding that it says will provide the capital required to move from late-stage development to market readiness. Venture fund
Age1
led the financing for the 7-year-old, San Francisco-based company.
Methodology
We tracked the largest announced rounds in the Crunchbase database that were raised by U.S.-based companies for the period of Feb. 7-13. Although most announced rounds are represented in the database, there could be a small time lag as some rounds are reported late in the week.
Illustration:
Dom Guzman
— Source: Crunchbase News (https://news.crunchbase.com/venture/biggest-funding-rounds-anthropic-leads-ai-robotics/)