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Nature Medicine

Neurodegenerative diseases need more mechanism-informed trials

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Nature Medicine, Published online: 16 February 2026; doi:10.1038/s41591-026-04258-0 Recent failures in high-profile clinical trials of neurodegenerative diseases highlight the need to rebalance clinical ambition and biological understanding.

Nature Medicine, Published online: 16 February 2026;

doi:10.1038/s41591-026-04258-0

Recent failures in high-profile clinical trials of neurodegenerative diseases highlight the need to rebalance clinical ambition and biological understanding.

— Source: Nature Medicine (https://www.nature.com/articles/s41591-026-04258-0)

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