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Nature Medicine

Innate antiviral and immune functions associated with the HIV reservoir decay after anti-PD-1 therapy

Rafick-Pierre Sekaly 2026-02-12 · Health, Health & Biotech
myndfocal
Nature Medicine, Published online: 12 February 2026; doi:10.1038/s41591-025-04139-y A follow-up analysis of a clinical trial that evaluated anti-PD-1 therapy in patients with cancer who are living with HIV provides mechanistic insights into transcriptomic, cellular and cytokine changes related to immune checkpoint inhibitor treatment and identifies a signature associated with clinical response.

Nature Medicine, Published online: 12 February 2026;

doi:10.1038/s41591-025-04139-y

A follow-up analysis of a clinical trial that evaluated anti-PD-1 therapy in patients with cancer who are living with HIV provides mechanistic insights into transcriptomic, cellular and cytokine changes related to immune checkpoint inhibitor treatment and identifies a signature associated with clinical response.

— Source: Nature Medicine (https://www.nature.com/articles/s41591-025-04139-y)

Health Health & Biotech
Read original on Nature Medicine →